Atlas of Ulcers in Systemic Sclerosis by Marco Matucci-Cerinic & Christopher P. Denton

Author:Marco Matucci-Cerinic & Christopher P. Denton
Language: eng
Format: epub
ISBN: 9783319984773
Publisher: Springer International Publishing

(2)Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

(3)Department of Geriatric Medicine, Division of Rheumatology, AOUC, Florence, Italy

Francesca Bartoli

Keywords

CalcinosisDystrophic calcificationSystemic sclerosisSclerodermaUlcerDigital pitting scarsSkin involvementCRESTSScRaynaud’s phenomenon

Definition

Calcinosis is a disorder characterized by deposition of calcium in the skin and subcutaneous tissues [1].

It is one of the typical manifestations of systemic sclerosis (SSc), especially in the limited cutaneous SSc (lcSSc) subtype, identified in 40% of patients and having a substantial impact on quality of life. Calcinosis is frequently associated with Raynaud’s phenomenon, esophageal alterations, sclerodactyly, and telangiectasia configuring the CREST syndrome.

It most commonly involves the hands, particularly the fingers, and it is often associated with pain, recurrent episodes of local inflammation, and functional impairment [1].

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